How Trivial is It to Make Amides?
Amide is one of the organic functional groups that can be found ubiquitously in the nature. It plays important role in living things as the main building blocks of proteins which involve with many functions, from catalysis to structural support. Besides that, amide functionality is featured in many natural products and drugs. Examples of peptide-bearing compounds Since, it is quite common to find this functionality in natural products and synthetic compounds, a question is raised from this phenomenon. How trivial is it to make amide bond?